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What is your experience of alcohol?

Hey everyone! Recently i've been out drinking with friends while taking modafinil mylan, without realising that there might be serious consequences to this. However, I have done it twice now and i'm still alive and didn't experience any negative side effects (e.g. blacking out, hangover, vomiting ect.) it is important to not that on both occasions I had over 2 standard drinks. It may be that fact that I had these drinks after 5pm and my last dose of modafinil is 12pm, yet, modafinil is said to have a 15 hour half-life in humans. All the literature I have read that discourage the use of modafinil seems to only focus on people who take it recreationally and don't have narcolepsy, so I'm wondering if, for a person with narcolepsy, it just normalised? Ultimately I'm wondering what your experiences are with alcohol and modafinil (or any other medication) because there is a disappointing lack of literature on the relationship between stimulants, narcolepsy and alcohol.

  1. Hi (Love your user name!). You ask some very good questions, but I am not sure there are any concrete answers. Every journey with narcolepsy is different, so everyone will react to alcohol differently. Add to that variable the level of sleep each person experienced that week or the night before, and the reaction to alcohol becomes even less predictable. Without factoring in medication, it is important to know how your body reacts to alcohol and how alcohol impacts your narcolepsy symptoms. Here is an article with some great tips for staying safe on nights out with friends: https://narcolepsy.sleep-disorders.net/living/tips-nightlife-safety. I thought it might interest you. As you know, the drug manufacturer warns against mixing alcohol with modafinil mylan (also known as Provigil), citing reports of reactions ranging from blackouts to significantly increased alcohol tolerance. Your non-reaction might be due to the decrease amount in your system or maybe you are one of those individuals whose tolerance improves when the two are mixed. The problem is that someone else might have a different experience, so their experience might not help you. Here is another article from one of our advocates who took methylphenidate with alcohol and blacked out: https://narcolepsy.sleep-disorders.net/living/mixing-alcohol-and-stimulants. Though modafinil mylan and methylphenidate are both stimulates used to treat EDS, they work differently. So, we can't even really compare the interactions with alcohol fairly. Here is a very detailed look at how modafinil reacts with alcohol in the body from the manufacturer: https://www.modafinil.com/modafinil-and-alcohol/. Essentially, every time you mix the two you are taking a chance. You might have no reaction or you might blackout. If you are with people you trust at all times, even while making trips to the restroom, and you don't drive, you are at least likely to be safe no matter what happens. You best bet would be to plan nights out in advance and either take your medication earlier so it is not in your system when you drink alcohol or don't take it on those days. I wish we had better answers and I hope others chime in with experiences. Warmest of wishes. - Lori (Team Member)

    1. Thank you so much Lori!! I think i'm gonna try skipping my second dose of the day and see what happens.

    2. Thay sounds like a good plan. Have fun, but stay safe! - Lori (Team Member)

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